SidaGhanaV1, Main, Exploration, bibRecord, 000487

First Susceptibility Testing of Mycobacterium tuberculosis for Second-line Anti-tuberculosis Drugs in Ghana

Identifieur interne : 000487 ( Main/Exploration ); précédent : 000486; suivant : 000488

First Susceptibility Testing of Mycobacterium tuberculosis for Second-line Anti-tuberculosis Drugs in Ghana

Auteurs : Tomoko Kato [Japon] ; Kennedy Kwasi Addo [Ghana] ; Naomi Nartey [Ghana] ; Alexander Kwadwo Nyarko [Ghana] ; Frank Adae Bonsu [Ghana] ; Satoshi Mitarai [Japon]

Source :

Tropical Medicine and Health [ 1348-8945 ] ; 2014.

RBID : PMC:3965846

Abstract

We performed drug susceptibility testing on first- and second-line drugs in Mycobacterium tuberculosis (M. tuberculosis) for the first time in Ghana to obtain preliminary data on drug-resistant tuberculosis. Of 21 isolates (4 new cases and 17 treated cases), 5 (23.8%) were multi-drug resistant tuberculosis (MDR-TB) and 19 (90.5%) were resistant to at least one drug, but no extensively drug-resistant TB (XDR-TB) was identified. Since the target patients were Category II, IV or smear positive at follow-up microscopy, it is understandable that there were many drug-resistant TB cases. Six isolates were resistant to one or two second-line drugs, but the second-line drugs were not approved in Ghana. It is considered that the bacilli were imported from abroad. Preventing the import of drug-resistant TB bacilli is probably one of best ways to control TB in Ghana.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965846

DOI: 10.2149/tmh.2013-16
PubMed: 24808747
PubMed Central: 3965846

Affiliations:

Le document en format XML

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Le SIDA au Ghana (serveur d'exploration)

First Susceptibility Testing of Mycobacterium tuberculosis for Second-line Anti-tuberculosis Drugs in Ghana

First Susceptibility Testing of Mycobacterium tuberculosis for Second-line Anti-tuberculosis Drugs in Ghana

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Abstract

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